Uranium Is Glowing, Biotech Is Breathing, and the Big Bank Is Back
By Steve Strazza
April 15, 2026
This note highlights a select group of stocks showing the most unusual — and highly directional — options activity.
The goal is simple: follow the big money and trade in the direction of the underlying trend.
Here is the list of Unusual Options activity from April 15:
*Click to enlarge view
Energy Fuels $UUUU — Uranium is back in focus. The domestic nuclear buildout is accelerating, and Energy Fuels is ramping output aggressively with long-term utility contracts already locked in through 2032.
Bullish flow showed up with 3,965 contracts of the 5/15 $30 calls, a big bet that the consolidation is about to resolve higher.
Arrowhead Pharmaceuticals $ARWR — Biotech is on fire, and Arrowhead is one of the names generating real conviction. The company just crossed its first FDA approval with plozasiran and has a full slate of Phase 3 readouts expected through the back half of this year.
Traders swept 328 contracts of the 9/18 $90 calls, positioning for a significant move as those catalysts approach.
Citigroup $C — Banks are reporting, and Citi just posted its best quarterly revenue in a decade — $24.6 billion in Q1 with EPS of $3.06. The turnaround story is no longer a question of "if" it's a question of how far.
Bullish flow came in with 10,032 contracts of the 5/15 $140 calls, the largest print in the table.
